{"id":14079,"date":"2022-10-20T12:31:51","date_gmt":"2022-10-20T12:31:51","guid":{"rendered":"https:\/\/jurmed.ro\/medici\/?p=14079"},"modified":"2022-10-20T12:31:51","modified_gmt":"2022-10-20T12:31:51","slug":"oncohub-2022-noi-directii-de-cercetare-si-colaborare-in-oncologie","status":"publish","type":"post","link":"https:\/\/jurmed.ro\/medici\/oncohub-2022-noi-directii-de-cercetare-si-colaborare-in-oncologie\/","title":{"rendered":"ONCOHUB 2022: noi direc\u021bii de cercetare \u0219i colaborare \u00een oncologie"},"content":{"rendered":"

A doua edi\u021bie a conferin\u021bei OncoHub s-a desf\u0103\u0219urat \u00een format hibrid \u2013 onsite (Hotel Escalade, Poiana Bra\u0219ov) \u0219i online \u00een perioada 21-23 septembrie 2022, fiind structurat\u0103 pe 11 sec\u021biuni tematice:<\/p>\n

1. cancere ale tractului gastro-intestinal,<\/p>\n

2. cancere de piele,<\/p>\n

3. cancere bronhopulmonare,<\/p>\n

4. cancere de s\u00e2n \u0219i ginecologice,<\/p>\n

5. cancere endocrine,<\/p>\n

6. cancere urogenitale,<\/p>\n

7. managementul pacientului cu cancer: o c\u0103l\u0103torie de la diagnostic la tratament,<\/p>\n

8. abord\u0103ri moderne \u00een cercetarea oncologic\u0103,<\/p>\n

9. nutri\u021bia \u00een cancer,<\/p>\n

10. oncohematologie \u0219i cancere pediatrice,<\/p>\n

11. cancere de cap \u0219i g\u00e2t, la acestea ad\u0103ug\u00e2ndu-se 2 sec\u021biuni de e-postere \u0219i 7 simpozioane.<\/p>\n

\nLectorii din \u021bar\u0103 \u0219i din str\u0103in\u0103tate au putut aduce la cuno\u0219tin\u021ba colegilor lor cele mai noi informa\u021bii despre cercet\u0103rile recente \u0219i tehnologiile de ultim\u0103 or\u0103 din domeniul oncologic pentru un mai bun management al pacien\u021bilor cu cancer, de la diagnosticare la reabilitare.<\/p>\n

Strategii de tratament<\/strong><\/p>\n

Conf. habil. dr. Octav Ginghin\u0103, Universitatea de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d, Institutul de Oncologie \u201eProf. Dr. Alexandru Trestioreanu\u201d, Spitalul de Oncologie Monza a adus \u00een discu\u021bie rolul tumor board \u00een managementul pacientului: \u201e\u00cen esen\u021b\u0103, tumorile neuroendocrine necesit\u0103 o echip\u0103 multidisciplinar\u0103. Nu pot fi gestionate f\u0103r\u0103 s\u0103 avem al\u0103turi de noi colegii oncologi \u0219i colegii endocrinologi.\u201d<\/em> Referindu-se la metodele de tratament pentru adenocarcinomul pancreatic versus tumorile neuroendocrine pancreatice, dr. Ioana Luca, IC Fundeni, Spitalul de Oncologie Monza, a remarcat c\u0103 \u201epentru tumorile neuroendocrine putem s\u0103 combin\u0103m, chiar \u0219i concomitent, toate metodele de tratament. Putem s\u0103 facem orice fel de procedur\u0103 loco-regional\u0103, s\u0103 intervenim chirurgical la orice moment al evolu\u021biei bolii, s\u0103 administr\u0103m inhibitori de tirozin-kinaza, dar obligatoriu vom p\u0103stra acest analog de somato-statine care sunt specifice tumorilor neuroendocrine. Dac\u0103 vorbim, \u00eens\u0103, de adenocarcinoamele pancreatice, lucrurile stau mult mai simplu \u2013 sunt rezecabile, ajunge la chirurg; nu sunt rezecabile sau sunt border rezecabile, atunci apar discu\u021bii relativ la utilitatea unui tratament neoadjuvant\u201d. Dr. Cosmin Bogdan T\u0103nase, manager, Institutul de Oncologie \u201eProf. Dr. Alexandru Trestioreanu\u201d, a subliniat \u00een prezentarea sa faptul c\u0103, pentru chirurgi, \u201ede baz\u0103 r\u0103m\u00e2ne diagnosticul precoce. Screeningul pentru cancer bronhopulmonar este bazat \u00een momentul de fa\u021b\u0103 pe CT low dose. Sunt \u021b\u0103ri care ofer\u0103 acest tip de screening \u0219i avem studii care arat\u0103 c\u0103 aceast\u0103 metod\u0103 diagnosticheaz\u0103 precoce boala, ceea ce ne-ar permite s\u0103 oferim tratament chirurgical, un tratament care, \u00een cazurile precoce, este unul curativ. Scopul tratamentului chirurgical este unul dublu, curativ \u0219i de staging. Acest staging poate oferi un tratament ulterior c\u00e2t mai corect\u201d<\/em>. O abordare interesant\u0103 \u00een ceea ce prive\u0219te provoc\u0103rile medicale \u0219i non-medicale \u00een practica privat\u0103 a avut dr. Dorin Bica, Spitalul de Oncologie Monza, care, plec\u00e2nd de la experien\u021ba pe care o are \u00een mediul privat, a atras aten\u021bia c\u0103 \u201ese poate observa c\u0103 exist\u0103 o schimbare de paradigm\u0103, \u00een sensul c\u0103 pacien\u021bii sunt foarte exigen\u021bi cu medicii, cu clinicile, iar acest lucru se va \u00eent\u00e2mpla aproape sigur \u00een spitalele publice \u00een urm\u0103torii cinci-zece ani\u201d<\/em>. Analiz\u00e2nd imunitatea SARS-CoV-2 la o cohort\u0103 de pacien\u021bi cu carcinom de cap \u0219i g\u00e2t, prof. dr. Petronela Ancu\u021ba, Universit\u00e9 de Montr\u00e9al, Quebec, Canada, \u0219i Universitatea din Bucure\u0219ti, Facultatea de Biologie, a prezentat un studiu care a avut ca scop de a monitoriza imunitatea umoral\u0103 dezvoltat\u0103 \u00een urma infec\u021biei cu SARS-CoV-2 sau a vaccin\u0103rii la un grup de pacien\u021bi cu cancer de cap \u0219i g\u00e2t (HNC). Astfel, cei 51 de participan\u021bii vaccina\u021bi \u0219i convalescen\u021bi recruta\u021bi de la Spitalul Col\u021bea (cohorta Col\u021bea COVID-19 HNC) au fost similari \u00een ceea ce prive\u0219te v\u00e2rsta, indicele de mas\u0103 corporal\u0103 (IMC) \u0219i timpul scurs de la imunizare. Concluzia studiului este c\u0103 pacien\u021bii cu HNC instaleaz\u0103 o imunitate umoral\u0103 eficient\u0103 \u00eempotriva SARS-CoV-2 la vaccinare sau infec\u021bia natural\u0103.<\/p>\n

\"\"<\/a>Instrumente moderne de diagnostic. Biopsia lichid\u0103 \u0219i endoscopia intraductal\u0103 \u00cen prezentarea sa, dr. Marius Zamfir, Institutul de Oncologie \u201eProf. Dr. Alexandru Trestioreanu\u201d, Spitalul de Oncologie Monza, a amintit c\u0103 sunt \u201ec\u00e2\u021biva factori predictivi care ar trebui s\u0103 ne atrag\u0103 aten\u021bia atunci c\u00e2nd avem o tumor\u0103 colorectal\u0103 stenozant\u0103 \u0219i s\u0103 ne \u00eentreb\u0103m dac\u0103 exist\u0103 o a doua forma\u021biune tumoral\u0103 care evident va schimba tactica chirurgical\u0103. Adic\u0103 instabilitatea microsatelitar\u0103, antigenul carcinoembrionar (CEA), istoricul familial de cancer colorectal \u0219i polipoza. Foarte important este s\u0103 avem \u00een vedere evaluarea la cel mult \u0219ase luni. Tumorile metacrone sunt, de fapt, de multe ori, tumori sincrone nediagnosticate. Aceast\u0103 limit\u0103 de timp de \u0219ase luni probabil c\u0103 este una relativ\u0103.<\/em>\u201d Dr. Zamfir a men\u021bionat \u0219i importan\u021ba dezvolt\u0103rii biopsiei lichide ca metode de prognostic \u0219i modulare a terapiei farmacologice \u00een cancerul colorectal. Pentru conf. dr. Theodor Voiosu, UMF \u201eCarol Davila\u201d, Spitalul Clinic Colentina, \u201ecolangiocarcinomul perihilar este un subiect foarte dificil de tratat \u0219i de abordat. Avem mai multe puncte de reper pentru to\u021bi cei care sunt implica\u021bi \u00een managementul acestor pacien\u021bi. De asemenea, avem \u00een momentul de fa\u021b\u0103 ni\u0219te instrumente de diagnostic noninvaziv extrem de performante \u2013 \u0219i RMN este \u00een prime time cu siguran\u021b\u0103 \u00een aceast\u0103 problem\u0103 \u2013, dar avem \u0219i instrumente invazive care sunt din ce \u00een ce mai performante. Vorbim \u00een special despre endoscopia intraductal\u0103, despre capacitatea noastr\u0103 de a examina direct tumorile \u0219i biopsia \u0219i de a le trata direct prin colangioscopie. Dar \u0219i prin tehnici adjuvante, a\u0219a cum este abla\u021bia prin radiofrecven\u021b\u0103, un instrument extrem de util intrat recent \u00een arsenalul endoscopi\u0219tilor<\/em>\u201d. Poten\u021bialul metastatic al melanomului cutanat este unul foarte crescut, fiind sus\u021binut de muta\u021bii genetice \u0219i de alter\u0103ri ale micro-mediului din cadrul tumorii, ceea ce face ca acest tip de cancer s\u0103 fie unul dintre cele mai letale, a amintit \u00een prezentarea studiului despre criteriile de diagnostic pentru evaluarea melanomului, cercet\u0103tor principal dr. \u0218tefana Petrescu, Institutul de Biochimie al Academiei Rom\u00e2ne. Melanoamele pigmentate pot fi recunoscute datorit\u0103 con\u021binutului ridicat de melanin\u0103, spre deosebire de melanoamele amelanotice, care nu au pigmentare \u0219i sunt de obicei diagnosticate \u00een stadii mai avansate.<\/p>\n

Viitorul 3D \u00een managementul cancerului: nanotransportori polimerci pentru medicamente antineoplazice<\/strong><\/p>\n

Prof. dr. C\u0103t\u0103lin Zaharia, Universitatea Politehnic\u0103 Bucure\u0219ti, a prezentat rolul \u0219i avantajele nanoparticulelor polimerice \u00een managementul cancerului plec\u00e2nd de la aplica\u021biile nanotehnologiei \u00een medicin\u0103 \u2013 nanomedicin\u0103, care este definit\u0103 ca fiind \u201eutilizarea nanomaterialelor pentru diagnostic, monitorizare, control, preven\u021bie \u0219i tratament al bolilor, bine\u00een\u021beles \u0219i \u00een managementul cancerului\u201d. Lector dr. Bianca G\u0103l\u0103\u021beanu, Universitatea din Bucure\u0219ti, Facultatea de Biologie, a vorbit despre importan\u021ba dezvolt\u0103rii unor sisteme de cultur\u0103 biomimetice \u201epentru a modela diferite tipuri de patologii \u0219i pentru a imita in vitro mai bine micro-mediul tumoral. Astfel, noi am dezvoltat mai multe tipuri de sisteme de cultur\u0103 3D pentru a studia patologia cancerului\u201d. \u0218i dr. Ariana Hudi\u021b\u0103, Universitatea din Bucure\u0219ti, Facultatea de Biologie, a abordat \u00een prezentarea sa aspecte ce \u021bin de modelele 3D de ultim\u0103 genera\u021bie: \u201eSistemele organ-on – a – chip sunt mult mai realiste \u0219i putem s\u0103 facem studii prin care putem s\u0103 mim\u0103m mult mai bine ce se \u00eent\u00e2mpl\u0103 \u00een organismul uman \u0219i nu numai. Putem s\u0103 cultiv\u0103m \u00een aceste chip-uri celule provenind de la pacien\u021bii no\u0219tri \u2013 \u0219i noi am \u00eenceput s\u0103 realiz\u0103m studii pe culturi primare care provin din tumori de la pacien\u021bi \u0219i care pot fi utilizate pentru modelarea a diferite patologii, nu numai a cancerului, c\u00e2t \u0219i pentru accelerarea procesului de dezvoltare de medicamente.\u201d<\/em><\/p>\n

Parteneriatul multidisciplinar \u00een comunitatea medical\u0103<\/strong><\/p>\n

\u201eConferin\u021ba OncoHub 2022 a subliniat importan\u021ba construirii de pun\u021bi de leg\u0103tura \u00eentre medici \u0219i speciali\u0219tii din diverse domenii biomedicale \u2013 cercet\u0103tori, ingineri, farmaci\u0219ti \u00een sprijinul progresului medicinei, al actului medical. OncoHub 2022 a demonstrat, prin prezent\u0103rile \u0219i dezbaterile generate, c\u0103 acest tip de unitate\/colaborare medici \u2013 cercet\u0103tori \u2013 farmaci\u0219ti \u2013 ingineri are multe avantaje, aduce idei originale care \u00eembun\u0103t\u0103\u021besc performan\u021bele \u0219i cuno\u0219tin\u021bele iar s\u0103n\u0103tatea pacientului poate fi, la r\u00e2ndul ei, \u00eembun\u0103t\u0103\u021bit\u0103 \u00een urma unui tratament cuprinz\u0103tor. Iat\u0103 de ce este nevoie de un parteneriat multidisciplinar \u00een comunitatea medical\u0103. Un alt doilea lucru important pe care OncoHub 2022 l-a eviden\u021biat \u021bine de eficientizare \u0219i, din nou, de colaborare. \u00cen cercetarea \u00een domeniul medical, rezultatele se difuzeaz\u0103 mai lent \u00een practic\u0103, \u00een partea clinic\u0103. Reducerea acestui decalaj, dintre cercetare \u0219i practic\u0103, este necesar\u0103 \u0219i dorit\u0103 \u0219i e posibil\u0103 prin dezvoltarea de departamente de cercetare \u00een interiorul spitalelor care ar u\u0219ura procesul de translatare a rezultatelor cercet\u0103rii \u00een practica de natur\u0103 clinic\u0103 \u0219i, \u00een acela\u0219i timp, ar u\u0219ura comunicarea \u0219i colaborarea dintre medicii clinicieni, chirurgi, oncologi \u0219i cercet\u0103tori. Punerea \u00een aplicare a transferului de cuno\u0219tin\u021be specifice activit\u0103\u021bii de cercetare \u00een oncologie, \u00een medicin\u0103 \u00een general, de la cercet\u0103tor la clinician ar u\u0219ura astfel ob\u021binerea unei \u00eengrijiri centrate pe pacient. Ne pregatim deja pentru urm\u0103toarea edi\u021bie a conferin\u021bei OncoHub \u0219i v\u0103 invit s\u0103 ne urm\u0103ri\u021bi pe canalele de socializare, FB \u0219i Instagram \u0219i pe site ul nostru, www.oncohub.ro pentru a afla mai multe detalii despre edi\u021bia 2023 \u00een cur\u00e2nd\u201d<\/em>, a declarat lector dr. Bianca G\u0103l\u0103\u021beanu, pre\u0219edinte conferin\u021ba OncoHub.<\/p>\n

OncoHub 2022 a \u00eenregistrat \u0219i c\u00e2teva cifre-record \u2013 743 de participan\u021bi, 73 onsite \u0219i 670 online; 68 de speakeri – 62 din Rom\u00e2nia \u0219i 6 interna\u021bionali (Grecia, Turcia, Spania, Italia, Fran\u021ba, SUA \u0219i Canada). De asemenea, OncoHub a fost un eveniment \u0219tiin\u021bific de \u00eenalt\u0103 \u021binut\u0103 creditat de Colegiul Medicilor din Rom\u00e2nia (CMR) cu 18 credite EMC, de Ordinul Biochimi\u015ftilor, Biologilor \u015fi Chimi\u0219tilor \u00een Sistemul Sanitar din Rom\u00e2nia (OBBCSSR) cu 18 credite EMC \u0219i de Colegiul Farmaci\u0219tilor din Rom\u00e2nia (CFR) cu 18 credite EFC.<\/p>\n

Conferin\u021ba OncoHub 2022 a fost organizat\u0103 sub egida Universit\u0103\u021bii de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d din Bucure\u0219ti \u0219i a Universit\u0103\u021bii din Bucure\u0219ti, \u00een parteneriat cu OncoTeam Diagnostic \u0219i Opteam, International Federation Of Clinical Chemistry and Laboratory Medicine, Prim\u0103ria Municipiului Bra\u0219ov.<\/p>\n","protected":false},"excerpt":{"rendered":"

A doua edi\u021bie a conferin\u021bei OncoHub s-a desf\u0103\u0219urat \u00een format hibrid \u2013 onsite (Hotel Escalade, Poiana Bra\u0219ov) \u0219i online \u00een perioada 21-23 septembrie 2022, fiind structurat\u0103 pe 11 sec\u021biuni tematice: […]<\/p>\n","protected":false},"author":4,"featured_media":14081,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-14079","post","type-post","status-publish","format-standard","has-post-thumbnail","category-stiri-noutati"],"yoast_head":"\nONCOHUB 2022: noi direc\u021bii de cercetare \u0219i colaborare \u00een oncologie - Jurmed - Medici<\/title>\n<meta name=\"description\" content=\"OncoHub fost organizat\u0103 sub egida Universit\u0103\u021bii de Medicin\u0103 \u0219i Farmacie \u201eCarol Davila\u201d din Bucure\u0219ti \u0219i a Universit\u0103\u021bii din Bucure\u0219ti, \u00een parteneriat cu OncoTeam Diagnostic\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jurmed.ro\/medici\/oncohub-2022-noi-directii-de-cercetare-si-colaborare-in-oncologie\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ONCOHUB 2022: noi direc\u021bii de cercetare \u0219i colaborare \u00een oncologie - 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