{"id":6470,"date":"2020-06-16T12:29:51","date_gmt":"2020-06-16T12:29:51","guid":{"rendered":"https:\/\/jurmed.ro\/pacienti\/?p=6470"},"modified":"2020-06-16T12:32:21","modified_gmt":"2020-06-16T12:32:21","slug":"ursomax-activator-filogenetic-de-microbiom","status":"publish","type":"post","link":"https:\/\/jurmed.ro\/pacienti\/ursomax-activator-filogenetic-de-microbiom\/","title":{"rendered":"URSOMAX – Activator filogenetic de microbiom"},"content":{"rendered":"
\"\"<\/a>
Autor: Dr. Sorin Godeanu Laboratoarele Elidor tel:0740167649<\/em><\/figcaption><\/figure>\n

Hibernarea reprezint\u0103 un exemplu emblematic despre inteligen\u021ba materiei vii, reprezentat\u0103 de ursul brun, un mamifer omnivor care traverseaz\u0103 o perioad\u0103 de cel pu\u021bin 6 luni (echivalent cu noaptea polar\u0103) \u00eentr-o loca\u021bie – ad\u0103post natural (scorbura), care-i asigur\u0103 numai protec\u021bie contra intemperiile naturii (v\u00e2nt, z\u0103pad\u0103, ploaie, etc), f\u0103r\u0103 hran\u0103 \u0219i lichide, ursul neav\u00e2nd mic\u021biuni \u0219i tranzit digestive \u00een toat\u0103 aceasta perioad\u0103. Surprinz\u0103tor, dup\u0103 6 luni de repaus total (hibernare), constat\u0103m c\u0103 ursul brun nu a f\u0103cut nici o complica\u021bie de tip tromboembolic, sarcopenie, osteoporoz\u0103, insuficien\u021b\u0103 cardiac\u0103, insuficien\u021b\u0103 respiratorie, insuficien\u021b\u0103 renal\u0103. \u00cen aceast\u0103 aventur\u0103 biologic\u0103 extrem\u0103, ursul este ajutat de o entitate p\u00e2n\u0103 nu demult neglijat\u0103-microbiomul, care reprezint\u0103 o comunitate complex\u0103 de microbi comensali, care descompun componentele unei diete diversificate \u0219i moduleaz\u0103 imunitatea nativ\u0103 \u0219i produce molecule semnal \u0219i metaboli\u021bi care pot influen\u021ba sistemul vegetativ la mamifere. Microbiomul are func\u021bie cheie \u00een metabolismul general, imunitate \u0219i rezisten\u021b\u0103 la colonizare. Microbiomul intestinal este implicat \u00een modularea comportamentului \u0219i func\u021biei cognitive prin efectul asupra metaboli\u021bilor neuroactivi.<\/p>\n

Lan\u021burile scurte de acizi gra\u0219i produ\u0219i de microbiom sunt importan\u021bi \u00een rela\u021bia microbim-gazd\u0103 \u0219i reprezint\u0103 o surs\u0103 de energie pentru enterocite \u0219i moduleaz\u0103 func\u021bia de barier\u0103 epitelial\u0103 a gazdei. Lipsa alimenta\u021biei \u00een cursul sezonului rece solicit\u0103 microbiomul, care se bazeaz\u0103 pe dieta gazdei pentru substratul metabolic \u0219i pe tractul intestinal influen\u021bat de nutrien\u021bii enterali \u0219i activitatea microbian\u0103. Acumularea de energie \u0219i transformarea \u00een gr\u0103sime, \u00een timpul verii, se organizeaz\u0103 cu ajutorul microbiomului, f\u0103r\u0103 s\u0103 se produc\u0103 rezisten\u021b\u0103 la insulin\u0103. Cercet\u0103ri sus\u021binute au dovedit c\u0103 microbiomul se modific\u0103 \u00een func\u021bie de sezon, iar acesta (microbiomul) induce acumulare de energie sub form\u0103 de gr\u0103simi. \u00cen cursul verii, ur\u0219ii devin obezi, dar \u00ee\u0219i men\u021bin starea de s\u0103n\u0103tate. Transplantul de microbiom din timpul verii de la ur\u0219i la \u0219oarecii germ free le transfer\u0103 caracteristici specifice sezonului estival (acumulare de gr\u0103simi f\u0103r\u0103 afectarea curbei glicemice).\u00a0 Aceast\u0103 constatare vine \u00een sprijinul contribu\u021biei microbiomului \u00een biologia hibern\u0103rii ursului brun.<\/p>\n

Energia \u00een cursul hibern\u0103rii se elibereaz\u0103 prin lipoliz\u0103. \u00cen timpul hibern\u0103rii, ur\u0219ii mobilizeaz\u0103 \u0219i oxideaz\u0103 gr\u0103simile ca strategie de supravie\u021buire \u00eenso\u021bit\u0103 de utilizarea sc\u0103zut\u0103 de glucoz\u0103 \u0219i folosirea ampl\u0103 de aminoacizi pentru gluconeogenez\u0103. Microbiomul poate fi factorul determinant pentru conceptul de obezitate fiziologic\u0103, \u00een cazul \u0219oarecilor germ free, coloniza\u021bi cu microbiomul de var\u0103, care a generat mai mult\u0103 adipozitate dec\u00e2t \u0219oarecii germ free, coloniza\u021bi cu microbiomul de iarn\u0103. Dac\u0103 pentru intrarea \u00een hibernare exist\u0103 un protocol preg\u0103titor, pentru crearea unui cadru metabolic adecvat pentru aceast\u0103 c\u0103l\u0103torie care dureaz\u0103 cel pu\u021bin 6 luni, pentru ie\u0219irea din hibernare exist\u0103 un alt protocol pe care ursul brun \u00eel aplic\u0103 exemplar.<\/p>\n

\"\"<\/a>\u00cen acest context, Allium Ursinum (Leurda), poate fi considerat un ACTIVATOR FILOGENETIC de microbiom. Ingestia lui \u00een momentul ie\u0219irii din hibernare constituie \u201eUN COD DE ACCES\u201c pentru setarea fiziologiei competi\u021bionale la acest animal s\u0103lbatic. Realiz\u0103m c\u0103 dup\u0103 6 luni, de repaus total, biologia ursului brun a func\u021bionat ca un sistem \u00eenchis (anurie + tranzit intestinal blocat), acumul\u00e2ndu-se produ\u0219i cataboli\u021bi \u0219i radicali liberi endogeni \u00een cantitate imens\u0103, iar eliminarea lor a devenit imperativ\u0103 pentru revenirea la o via\u021b\u0103 normal\u0103 \u00eentr-un mediu provocator \u0219i ostil. Este important de specificat c\u0103 Allium Ursinum apare spa\u021bio temporal exact \u00een perioada \u00een care ursul brun iese din hibernare (am putea vorbi de o simbioz\u0103 perfect\u0103: plant\u0103-animal \u00een lupta pentru supravie\u021buire \u0219i continuarea speciei).<\/p>\n

Allium Ursinum dispune de compu\u0219i organo-sulfura\u021bi: sulfoxizi \u0219i tiosulfi\u021bi, care sunt instabili \u0219i se descompun \u00een polisulfi\u021bi, ditiine, ajoene, fenoli, flavonoizi (inhibitori de agregare plachetar\u0103). Allium Ursinum este spamolitic, antimicrobian, antioxidant folosit\u0103 \u00een medicina tradi\u021bional\u0103 pentru cefalee, HTA, ateroscleroz\u0103, diaree, boli pulmonare (spectru antibacterian \u0219i antifungic).\u00a0 Mai men\u021bion\u0103m alte calit\u0103\u021bi terapeutice: antibacterian, antitrombotic, antitumoral, antihiperlipemic, hipoglicemic, depurativ, diaforetic, expectorant, vasodilatator. Un efect esen\u021bial este inhibi\u021bia de sintez\u0103 de NO prin care se reduce r\u0103spunsul inflamator (EFECT INHIBITOR ASUPRA STRESULUI NITRO-OXIDATIV).<\/p>\n

Allium Ursinum reprezint\u0103 componentul pivot \u00een produsul URSOMAX (ELIDOR). Acest produs a fost folosit \u00eentr-o serie de protocoale terapeutice pentru pacien\u021bii din terapie intensiv\u0103, interna\u021bi pentru traume neuro-chirurgicale, politraume, accidente vasculare cerebrale, pneumopatii de sine st\u0103t\u0103toare sau \u00een cadrul bolilor mai sus men\u021bionate (pneumonia de aspira\u021bie). Majoritatea bolnavilor au fost \u00een stare critic\u0103 cu disfunc\u021bii de organ (pl\u0103m\u00e2n, cord, rinichi, sistem nervos, hematologie). O caracteristic\u0103 la ace\u0219ti pacien\u021bi a fost limfopenia la internarea\u00a0 \u00een STI.<\/p>\n

Administrarea de URSOMAX, \u00een cadrul protocolului complex, a confirmat valoarea terapeutic\u0103 a produsului prin evolu\u021bia favorabil\u0103 a pacien\u021bilor trata\u021bi. Administrarea de URSOMAX, a fost poten\u021bat\u0103 prin combinarea cu DEPUREX \u0219i PUROFORT. Doza uzual\u0103 de URSOMAX a fost de 4-8 tablete\/zi. Nu s-au men\u021bionat incompatibilit\u0103\u021bi. Suntem convin\u0219i c\u0103 microbiomul reprezint\u0103 o leg\u0103tur\u0103 de siguran\u021b\u0103 cu parcursul filogenetic de la organismele cele mai simple la cele mai complexe \u0219i ca identificarea de al\u021bi activatori de microbiom poate genera rezultate terapeutice pe care \u00een momentul actual nu le putem evalua la adev\u0103rata lor valoare.<\/p>\n

LABORATOARELE ELIDOR<\/em><\/p>\n

Tel: 021.335.95.63, 021.336.77.78<\/strong><\/em><\/p>\n

www.elidor.ro; email: office@elidor.ro<\/strong><\/em><\/p>\n

Pentru preciz\u0103ri \u015fi informa\u0163ii suplimentare consulta\u0163i site-ul:\u00a0 secreteledoctorului.wordpress.com<\/u><\/em><\/p>\n

\n","protected":false},"excerpt":{"rendered":"

Hibernarea reprezint\u0103 un exemplu emblematic despre inteligen\u021ba materiei vii, reprezentat\u0103 de ursul brun, un mamifer omnivor care traverseaz\u0103 o perioad\u0103 de cel pu\u021bin 6 luni (echivalent cu noaptea polar\u0103) \u00eentr-o […]<\/p>\n","protected":false},"author":4,"featured_media":6474,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[126],"tags":[],"class_list":["post-6470","post","type-post","status-publish","format-standard","has-post-thumbnail","category-terapii-naturale"],"yoast_head":"\nURSOMAX - Activator filogenetic de microbiom - Jurmed - Pacienti<\/title>\n<meta name=\"description\" content=\"URSOMAX este un activator filogenetic de microbiom folosit pentru pacien\u021bii din ATI, pentru traume neuro-chirurgicale, politraume, accidente vasculare\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jurmed.ro\/pacienti\/ursomax-activator-filogenetic-de-microbiom\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"URSOMAX - 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