{"id":7646,"date":"2021-06-16T11:55:59","date_gmt":"2021-06-16T11:55:59","guid":{"rendered":"https:\/\/jurmed.ro\/pacienti\/?p=7646"},"modified":"2021-06-16T11:55:59","modified_gmt":"2021-06-16T11:55:59","slug":"lipozomal-glutation-maestrul-antioxidant","status":"publish","type":"post","link":"https:\/\/jurmed.ro\/pacienti\/lipozomal-glutation-maestrul-antioxidant\/","title":{"rendered":"Lipozomal Glutation, maestrul antioxidant"},"content":{"rendered":"
\"\"<\/a>
Autor: Farmacist primar Iuliana Vasilache Hyperfarm Ia\u0219i Tel.0754045411 office@hyperfarm.ro www.hyperfarm.ro<\/em><\/figcaption><\/figure>\n

Celulele \u0219i \u021besuturile umane sunt uria\u0219e uzine \u00een care sunt procesate milioane de reac\u021bii biochimice. C\u0103 \u00een orice uzin\u0103, zilnic rezult\u0103 o multitudine de de\u0219euri ce necesit\u0103 a fi neutralizate \u0219i \u00eendep\u0103rtate.<\/p>\n

Radicalii liberi sunt structuri ce apar din abunden\u021b\u0103 \u00een urma acestor procese biochimice \u0219i produc deterior\u0103ri ale structurilor celulare. Excesul de radicali liberi \u0219i agresiunea acestora asupra \u021besuturilor \u0219i organelor sunt cunoscute sub denumirea de stres oxidativ.<\/p>\n

Diminuarea nivelului de glutation (GSH)\u00a0 provoac\u0103 daune grave<\/u><\/strong><\/p>\n

Radicalii liberi \u0219i implicit stresul oxidativ sunt profund implica\u021bi \u00een apari\u021bia \u0219i dezvoltarea bolilor cardiovasculare, bolilor inflamatorii, artritei, fibrozei pulmonare sau a bolilor neurodegenerative precum Alzheimer, Parkinson, diverselor forme de cancer, \u00eemb\u0103tr\u00e2nirea prematur\u0103 a \u021besuturilor prin pierderea rezisten\u021bei \u0219i elasticit\u0103\u021bii acestora.<\/p>\n

Num\u0103rul radicalilor liberi este cu at\u00e2t mai mare cu c\u00e2t organismul este expus polu\u0103rii, alimentelor procesate, infec\u021biilor virale \u0219i bacteriene, stresului, fumatului, medicamentelor, metalelor grele, etc.<\/p>\n

Glutationul GSH este o molecul\u0103 omniprezent\u0103 \u00een celule \u0219i \u021besuturi \u00een concentra\u021bii ridicate (de 2-5 mMoli) ce are rol de tampon redox intracelular. Fiecare celul\u0103 din corp are nevoie de un nivel constant, echilibrat de GSH pentru a-\u0219i asigura o eficient\u0103 ap\u0103rare antioxidant\u0103.<\/p>\n

Din p\u0103cate, concentra\u021bia de GSH se diminueaz\u0103 odat\u0103 cu \u00eemb\u0103tr\u00e2nirea, iar b\u0103rba\u021bii au niveluri mai sc\u0103zute comparativ cu femeile. S-a demonstrat c\u0103 \u00een cazul infec\u021biilor severe cu COVID-19 nivelul GSH este sc\u0103zut iar cre\u0219terea nivelului de GSH ar putea fi o op\u021biune pentru a reduce num\u0103rul pacien\u021bilor simptomatici precum \u0219i pentru ameliorarea crizelor respiratorii acute cauzate de bronhopneumonii.<\/p>\n

Studiile arat\u0103 c\u0103 majoritatea bolilor cardiovasculare, AVC, diabetului, fibrozelor chistice, infec\u021biilor, autismului, schizofreniei, bolilor Alzheimer \u0219i Parkinson sunt asociate cu epuizarea intracelular\u0103 a Glutationului, combinat\u0103 cu diferite st\u0103ri de stres oxidativ.<\/p>\n

\"\"<\/a>Glutationul \u00een regenerarea \u021besuturilor afectate de stresul oxidativ<\/u><\/strong><\/p>\n

Cercet\u0103rile au demonstrat c\u0103 suplimentarea cu Glutation este eficace \u00een diverse patologii, iar cele mai bune rezultate au fost observate \u00een diabet, bolile cardiovasculare, pulmonare \u0219i virale.<\/p>\n

Literatura de specialitate arat\u0103 c\u0103 aportul de GSH este eficient \u00een infarctul miocardic acut (prin reducerea marker-ilor inflamatorii), \u00een sc\u0103derea tensiunii arteriale la hipertensivi \u0219i diabetici (prin interac\u021biunea cu radicalii liberi de oxid nitric) \u0219i \u00een ameliorarea fibrozei pulmonare (prin atenuarea stresului oxidativ).<\/p>\n

Glutationul administrat oral a avut efecte benefice \u00een cazurile de steatoz\u0103 hepatic\u0103, \u00een m\u0103rirea capacit\u0103\u021bii de ardere a gr\u0103similor, \u00een \u00eencetinirea evolu\u021biei bolii Parkinson \u0219i \u00een diminuarea degrad\u0103rii oxidative la nivel cerebral la copiii cu autism.<\/p>\n

Glutationul exist\u0103 sub dou\u0103 forme, una redus\u0103 \u0219i una oxidat\u0103, dar numai forma redus\u0103 este bioactiv\u0103.<\/p>\n

Suplimentarea cu GSH este o abordare promi\u021b\u0103toare, dar din p\u0103cate, este o molecul\u0103 cu grad sc\u0103zut de absorb\u021bie \u0219i ar fi nevoie de doze prea mari pentru a ob\u021bine eficacitate terapeutic\u0103. Solu\u021bia este \u00eencapsularea \u00een lipozomi a formei bioactive de glutation, fiind singura form\u0103 de administrare oral\u0103 prin care se asigur\u0103 absorb\u021bia rapid\u0103 \u0219i concentra\u021bie seric\u0103 ridicat\u0103. Lipozomii protejeaz\u0103 glutationul \u00een mediul intestinal, astfel \u00eenc\u00e2t acesta nu este deteriorat, fiind transportat \u0219i absorbit rapid la nivel celular.<\/p>\n

Men\u021binerea unui nivel ridicat de Glutation este o necesitate pentru omul modern, expus polu\u0103rii fizice, chimice, emo\u021bionale, electromagnetice, medicamentoase, ce induce un stres oxidativ major cu repercusiuni vizibile \u00een starea noastr\u0103 de s\u0103n\u0103tate (explozia de boli cardiovasculare, tumorale, psihice etc).<\/p>\n

Asocierea Lipozomal Glutation<\/strong> cu Lipozomal B12+D-Riboza<\/strong> constituie un sprijin important pentru cre\u0219terea energiei cardiace, \u00eembun\u0103t\u0103\u021birea func\u021biilor pulmonare a activit\u0103\u021bii fizice \u0219i a calit\u0103\u021bii vie\u021bii.<\/p>\n","protected":false},"excerpt":{"rendered":"

Celulele \u0219i \u021besuturile umane sunt uria\u0219e uzine \u00een care sunt procesate milioane de reac\u021bii biochimice. C\u0103 \u00een orice uzin\u0103, zilnic rezult\u0103 o multitudine de de\u0219euri ce necesit\u0103 a fi neutralizate […]<\/p>\n","protected":false},"author":4,"featured_media":7649,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[99],"tags":[],"class_list":["post-7646","post","type-post","status-publish","format-standard","has-post-thumbnail","category-oncologie"],"yoast_head":"\nLipozomal Glutation, maestrul antioxidant - Jurmed - Pacienti<\/title>\n<meta name=\"description\" content=\"Lipozomal Glutation constituie un sprijin important pentru cre\u0219terea energiei cardiace, \u00eembun\u0103t\u0103\u021birea func\u021biilor pulmonare, a activit\u0103\u021bii fizice\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jurmed.ro\/pacienti\/lipozomal-glutation-maestrul-antioxidant\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lipozomal Glutation, maestrul antioxidant - 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