{"id":8306,"date":"2022-02-07T14:08:38","date_gmt":"2022-02-07T14:08:38","guid":{"rendered":"https:\/\/jurmed.ro\/pacienti\/?p=8306"},"modified":"2022-02-07T14:09:08","modified_gmt":"2022-02-07T14:09:08","slug":"fierul","status":"publish","type":"post","link":"https:\/\/jurmed.ro\/pacienti\/fierul\/","title":{"rendered":"C\u00e2nd fierul nu este de ajuns"},"content":{"rendered":"
\"\"<\/a>
Autor: Dr. Lumini\u021ba Paraschiv, Medical Affairs Manager Prisum<\/em><\/figcaption><\/figure>\n

De\u015fi cantitatea total\u0103 de fier din corpul nostru este de doar 3-4 g, acest mineral \u00eendepline\u015fte roluri esen\u0163iale pentru organism. <\/strong><\/p>\n

Fierul se reg\u0103se\u015fte \u00een procent de aproximativ 70% \u00een interiorul globulelor ro\u015fii, unde intr\u0103 \u00een compozi\u0163ia hemoglobinei. Hemoglobina este proteina care d\u0103 culoarea ro\u015fie a s\u00e2ngelui \u015fi care are rolul de a transporta oxigenul. La r\u00e2ndul s\u0103u, oxigenul este utilizat de celule pentru a furniza energie, \u00een urma procesului de respira\u0163ie aerob\u0103. De aceea, pacien\u0163ii cu anemie, afec\u021biune caracterizat\u0103 printr-un nivel sc\u0103zut de hemoglobin\u0103, prezint\u0103 paloare, st\u0103ri de oboseal\u0103, ame\u0163eal\u0103, palpita\u0163ii \u0219i lipsa rezisten\u021bei la efort.<\/p>\n

Fierul este deosebit de important \u015fi pentru sus\u0163inerea sistemului imunitar \u015fi a func\u0163iilor cognitive, astfel c\u0103 un deficit de fier poate fi corelat cu cre\u015fterea episoadelor de infec\u0163ii, dar \u015fi cu afectarea memoriei, a capacit\u0103\u0163ii de \u00eenv\u0103\u0163are sau a comportamentului.<\/p>\n

Caren\u021ba de fier este cea mai r\u0103sp\u00e2ndit\u0103 deficien\u021b\u0103 nutri\u0163ional\u0103 la nivel mondial \u015fi este principala cauz\u0103 a anemiei. Se estimeaz\u0103 ca anemia feripriv\u0103 reprezint\u0103 jumatate din cazurile totale de anemie. Totu\u0219i, \u00een mod normal, nu avem nevoie de un aport foarte mare de fier \u00eentruc\u00e2t organismul are abilitatea de a refolosi acest element, prelu\u00e2ndu-l din eritrocitele moarte. De aceea, corpul nostru are o capacitate limitat\u0103 de a absorbi fierul din alimente sau suplimente. Se apreciaz\u0103 ca necesarul zilnic de fier este de 14 mg, astfel c\u0103, administrarea oral\u0103 a unor cantit\u0103\u0163i mari de fier este nu doar inutil\u0103, dar \u015fi generatoare de reac\u0163ii adverse gastrointestinale de tip grea\u0163\u0103 \u015fi constipa\u0163ie, \u00eentruc\u00e2t fierul neabsorbit se elimin\u0103 digestiv. \u00cen cazul administr\u0103rii fierului sub forma oral\u0103, mai mult nu \u00eenseamn\u0103 \u00eentotdeauna mai bine!<\/p>\n

\u00cen plus, nu este de ajuns s\u0103 utiliz\u0103m doar fier dac\u0103 vrem s\u0103 prevenim anemia, \u00eentruc\u00e2t fierul nu este solitar \u00een \u00eendeplinirea func\u0163iilor sale. Exist\u0103 o serie de \u201ccoechipieri\u201d care intervin \u00een absorb\u0163ia \u015fi utilizarea fierului, precum \u015fi \u00een sinteza hemoglobinei \u015fi a globulelor ro\u015fii.<\/p>\n

\"\"<\/a>Vitamina B12 are un rol important \u00een sinteza normal\u0103 a globulelor ro\u015fii \u015fi \u00een producerea de energie. Aceasta vitamin\u0103 poate fi procurat\u0103 doar din alimentele de origine animal\u0103, astfel c\u0103 persoanele care adopt\u0103 o alimenta\u0163ie vegan\u0103 trebuie s\u0103 \u00ee\u015fi asigure necesarul de vitamina B12 din suplimente. Nivelul redus de vitamina B12 poate fi determinat \u015fi de absorb\u021bia redus\u0103, pe fondul unor afec\u0163iuni gastrointestinale, \u00eent\u00e2lnite frecvent la v\u00e2rstnici. Acidul folic (vitamina B9) intervine \u00een procesul de diviziune celular\u0103, fiind necesar pentru sinteza normal\u0103 a celulelor noi, inclusiv a globulelor ro\u015fii. Deficitul de vitamina B12 \u015fi\/sau de acid folic determin\u0103 un alt tip de anemie, numit\u0103 anemia megaloblastic\u0103, caracterizat\u0103 prin modific\u0103ri morfologice ale eritrocitelor.<\/p>\n

Vitamina B6 \u015fi acidul pantotenic (vitamina B5) sunt alte dou\u0103 vitamine cu rol important \u00een metabolismul proteinelor \u015fi \u00een formarea hemoglobinei, \u00een generarea de energie \u015fi \u00een combaterea st\u0103rii de oboseal\u0103. Mai pu\u0163in cunoscut este rolul zincului \u015fi al cuprului \u00een combaterea anemiei, oligoelemente care intr\u0103 \u00een structura multor enzime, inclusiv a celor cu rol \u00een formarea globulelor ro\u015fii. Astfel, zincul are rol important \u00een metabolismul fierului, iar studii recente au scos \u00een eviden\u0163\u0103 faptul ca pacien\u0163ii cu anemie feripriv\u0103 au adesea \u015fi deficit de zinc. La r\u00e2ndul s\u0103u, cuprul cre\u015fte absorb\u0163ia fierului din intestin \u015fi ajut\u0103 la fixarea sa \u00een hemoglobin\u0103. Deficitul de cupru poate conduce la sc\u0103derea fierului din organism \u0219i instalarea anemiei, care nu se va putea corecta prin administarea de fier.<\/p>\n

\u00a0Este bine de \u0219tiut c\u0103 zincul \u015fi cuprul au o rela\u0163ie de rivalitate \u00een ceea ce prive\u015fte absorb\u0163ia din intestin. Speciali\u015ftii atrag aten\u0163ia c\u0103 administrarea zincului \u00een doze mari, pe termen lung, \u00een scopul cre\u015fterii imunit\u0103\u0163ii, inclusiv \u00een contextul COVID-19, poate conduce la anemia prin deficit de cupru.<\/p>\n

Sinteza globulelor ro\u015fii este o munc\u0103 de echip\u0103, \u00een care fierul, de\u0219i are un rol important, nu este de ajuns, ci trebuie combinat, \u00eentr-un echilibru perfect, cu o serie de vitamine \u015fi minerale. Absen\u0163a unui singur element rupe acest echilibru \u015fi \u00eempiedic\u0103 ob\u0163inerea unor eritrocite s\u0103n\u0103toase, av\u00e2nd drept consecin\u0163\u0103 instalarea anemiei \u0219i privarea celulelor de oxigen.<\/p>\n","protected":false},"excerpt":{"rendered":"

De\u015fi cantitatea total\u0103 de fier din corpul nostru este de doar 3-4 g, acest mineral \u00eendepline\u015fte roluri esen\u0163iale pentru organism. Fierul se reg\u0103se\u015fte \u00een procent de aproximativ 70% \u00een interiorul […]<\/p>\n","protected":false},"author":4,"featured_media":8308,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[474],"tags":[],"class_list":["post-8306","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medicina-interna"],"yoast_head":"\nC\u00e2nd fierul nu este de ajuns - Jurmed - Pacienti<\/title>\n<meta name=\"description\" content=\"Fierul este deosebit de important \u015fi pentru sus\u0163inerea sistemului imunitar \u015fi a func\u0163iilor cognitive.Caren\u021ba de fier este cea mai r\u0103sp\u00e2ndit\u0103\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jurmed.ro\/pacienti\/fierul\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"C\u00e2nd fierul nu este de ajuns - 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